Assessment of the Microbiota in Microdissected Tissues of Crohn's Disease Patients

Table 5

Distribution of bacterial taxa over the 33 tissue samples (*) (**).

Identification	CD					Disease controls						Healthy controls
	IL, normal mucosa (samples 1–4)	IL+COL, pathological mucosa (samples 5–8)	IL+COL, ulcer (samples 9–11)	IL+COL, myenteric plexus (samples 12–15)	lymph node (samples 16–19)	COL, ASLC (sample 20)	COL, ASLC (sample 21)	COL, PMC (sample 22)	COL, PMC (sample 23)	COL, DIV (sample 24)	COL, DIV (sample 25)	IL, normal mucosa (sample 26)	COL, normal mucosa (samples 17–29)	IL, myenteric plexus (sample 30)	COL, myenteric plexus (samples 31–33)
Total number of sequences; (domain bacteria)	18	22	52	45	79	15	14	12	7	40	38	1	24	35	8
Phylum XII. Proteobacteria
Class III. Gammaproteobacteria
Order III. Xanthomonadales
Family I. Xanthomonadaceae				11
Order VI. Legionellales
Family I. Legionellaceae				51
Order IX. Pseudomonadales
Family II. Moraxellaceae				18
Order XII. Aeromonadales
Family II. Succinivibrionaceae					1
Order XIII. Enterobacteriales
Family I. Enterobacteriaceae	56	68	67		15	53				5	32	100
Escherichia coli					43					95
Order XIV. Pasteurellales
Family I. Pasteurellaceae					1						8
Class V. Epsilonproteobacteria
Order I. Campylobacterales
Family I. Campylobacteraceae								8
Phylum XIII. Firmicutes
Class I. Clostridia
Order I. Clostridiales
Family I. Clostridiaceae	28				13			8			8
Clostridium nexile					1
Family II. Lachnospiraceae	11	5			5						18
Family IV. Eubacteriaceae					1						8
Eubacterium rectale											16
Family VII. Acidaminococcaceae			33								3
Class III. Bacilli
Order I. Bacillales
Family I. Bacillaceae							7								100
Order II. Lactobacillales
Family I. Lactobacillaceae							7	8
Lactobacillus rhamnosus									100
Family IV. Enterococcaceae							21
Enterococcus faecalis							64
Family VI. Streptococcaceae				4				8			3		50
Streptococcus mitis								58
Phylum XIV. Actinobacteria
Class I. Actinobacteria
Order I. Actinomycetales
Family I. Micrococcaceae														9
Kocuria rosea				2										74
Family I. Propionibacteriaceae				13										3
Propionibacterium acnes	6	27												14
Phylum XX. Bacteroidetes
Class I. Bacteroidetes
Order I. Bacteroidales
Family I. Bacteroidaceae					14	7					3		50
Bacteroides fragilis					4
Bacteroides eggerthii								8
Bacteroides uniformis											3
Family III. Porphyromonadaceae					1
Family IV. Prevotellaceae						40

(*) Numbers indicated per taxon are percentages of the total number of sequences indicated in the first row.
(**) Empty cells indicate value of 0%.