Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation
Figure 1
SUMOylation process. Protein SUMOylation consists of deconjugation and conjugation pathways. SUMO-conjugation requires three classes of enzymes (E1 E2 E3). SUMO-deconjugation requires the sentrin/SUMO-specific proteases (SENP2).