Table of Contents Author Guidelines Submit a Manuscript
International Journal of Inflammation
Volume 2012, Article ID 907078, 6 pages
Review Article

The Role of S100A12 as a Systemic Marker of Inflammation

1Departments of Paediatrics and Medicine, University of Otago-Christchurch, P.O. Box 4345, Christchurch 8140, New Zealand
2Departments of Paediatrics and Gastroenterology, Christchurch Hospital, Christchurch 8140, New Zealand

Received 29 March 2012; Revised 17 May 2012; Accepted 17 May 2012

Academic Editor: Juan Carlos Kaski

Copyright © 2012 B. Meijer et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


S100A12 is a member of the S100 family of calcium-binding proteins with important extracellular activities. In recent years, investigators across a number of fields have delineated the patterns of S100A12 expression in a variety of conditions. These data suggest that S100A12 can be used as a valuable serum inflammatory marker.