Circulating Anti-Beta2-Glycoprotein I Antibodies Are Associated with Endothelial Dysfunction, Inflammation, and High Nitrite Plasma Levels in Patients with Intermittent Claudication

Table 1

Baseline characteristics of peripheral arterial disease patients according to circulating anti-beta2-glycoprotein I antibodies titer.

	ABGPI titer ≥1 : 10% (𝑛=21)	ABGPI titer <1 : 10% (𝑛=29)	𝑃 value
Age and cardiovascular risk factors
Age (years)	65 [60–67]	66 [61–71]	0.58
Diabetes mellitus	6 [29%]	7 [24%]	0.72
History of Smoking	9 [43%]	12 [41%]	0.91
Coronary heart disease	3 [14%]	7 [24%]	0.48
Hypertension	12 [57%]	18 [62%]	0.72
Hyperlipidemia	14 [68%]	16 [55%]	0.41
Cerebrovascular disease	3 [14%]	2 [7%]	0.63
Chronic renal failure	2 [9%]	1 [3%]	0.56
Chronic pulmonary disease	1 [5%]	2 [7%]	1
Medical treatment
Antiplatelet	13 [62%]	20 [69%]	0.60
Statins	9 [43%]	6 [21%]	0.91
ACE inhibitors	11 [52%]	15 [52%]	0.96
Nitrates	1 [5%]	5 [17%]	0.38
Beta-blockers	2 [9%]	4 [14%]	1
Calcium antagonist	5 [24%]	10 [34%]	0.41
Beta-agonists	2 [9%]	2 [7%]	1
Oral anticoagulants	0 [0%]	3 [10%]	0.25

ABGPI: Anti-beta2-glycoprotein I antibodies.