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International Journal of Inflammation
Volume 2013, Article ID 438412, 6 pages
Review Article

Inflammation in Retinal Vein Occlusion

Department of Ophthalmology, Columbia University Medical Center, New York, NY 10032, USA

Received 31 January 2013; Accepted 5 March 2013

Academic Editor: David A. Hollander

Copyright © 2013 Avnish Deobhakta and Louis K. Chang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Retinal vein occlusion is a common, vision-threatening vascular disorder. The role of inflammation in the pathogenesis and clinical consequences of retinal vein occlusion is a topic of growing interest. It has long been recognized that systemic inflammatory disorders, such as autoimmune disease, are a significant risk factor for this condition. A number of more recent laboratory and clinical studies have begun to elucidate the role inflammation may play in the molecular pathways responsible for the vision-impairing consequences of retinal vein occlusion, such as macular edema. This improved understanding of the role of inflammation in retinal vein occlusion has allowed the development of new treatments for the disorder, with additional therapeutic targets and strategies to be identified as our understanding of the topic increases.