Vasospasm in Cerebral Inflammation

Figure 1

Mechanism for induction of cerebral vasospasm by interleukin-1 (GPCR = G-protein coupled receptor, PKC = protein kinase C, MLCK = myosin light chain kinase, MLC = myosin light chain, MBS = myosin-binding subunit of myosin light chain phosphatase, MLCPh = myosin light chain phosphatase, -P indicates phosphorylated state, PLC = phospholipase C, and IP3 = phosphatidylinositol trisphosphate).