Live Combined Bacillus subtilis and Enterococcus faecium Ameliorate Murine Experimental Colitis by Immunosuppression
Figure 2
The expressions of TLRs in groups. (a) Immunochemistry of TLRs expressions in groups. (b) The mean numbers of positive cells per square millimeter of TLRs expressions were quantificated. (c) qRT-PCR analyzed the mRNA expressions of TLRs in groups. TLR2 and TLR4 were lowly expressed in normal intestinal tissues, while TLR9 was rarely expressed. After the establishment of experimental colitis, the expressions of TLR2, TLR4, and TLR9 were enhanced in the inflammatory cells which were located in lamina propria and submucosa. But after the treatment of Medilac-S the expressions of TLR2, TLR4, and TLR9 were all weakened. And the mRNA expressions in groups had the similar phenomenon ( per group; *compared with normal group, #compared with control group, * or #, ** or ## and *** or ###).
