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International Journal of Inflammation
Volume 2015, Article ID 316235, 9 pages
Review Article

Curbing Inflammation in Skin Wound Healing: A Review

Division of Plastic Surgery, Department of Surgery and Anatomy, Ribeirão Preto School of Medicine, University of São Paulo, Avenida Bandeirantes 3900, 14048-900 Ribeirão Preto, SP, Brazil

Received 15 March 2015; Revised 24 July 2015; Accepted 27 July 2015

Academic Editor: B. L. Slomiany

Copyright © 2015 Rodrigo G. Rosique et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Wound healing is a complex regulated process that results in skin scar formation in postnatal mammals. Chronic wounds are major medical problems that can confer devastating consequences. Currently, there are no treatments to prevent scarring. In the early fetus wounds heal without scarring and the healing process is characterized by relatively less inflammation compared to adults; therefore, research aimed at reducing the inflammatory process related to wound healing might speed healing and improve the final scar appearance.