Inflammatory Serum Protein Profiling of Patients with Lumbar Radicular Pain One Year after Disc Herniation

Table 2

List of biomarkers which are significantly differentially expressed when the false discovery rate (FDR) is 0.10 and 0.05. The rightmost column shows the estimated increase on the original non-log scale.

Biomarker	value	FDR adjusted value	Estimated increase
MCP-3/CCL7	0.0006	0.047	50.6%
M-CSF/CSF-1	0.001	0.047	20.2%
VEGF-A	0.0015	0.047	47.6%
CXCL10/IP10	0.0017	0.047	55.2%
MCP-2	0.0023	0.047	56.6%
CXCL5	0.0024	0.047	217.0%
CCL-4	0.0034	0.047	43.4%
IL-15-R-alpha	0.0036	0.047	15.2%
MCP-4	0.004	0.047	69.9%
TGF-beta-1	0.0041	0.047	52.3%
CASP-8	0.0051	0.047	14.3%
EGF	0.0064	0.047	142.0%
STAMPB	0.0071	0.047	40.4%		FDR < 0.05
IFNg	0.0102	0.0553	25.0%
IL-6	0.0118	0.0596	68.5%
TRAIL	0.0119	0.0596	16.6%
LIGHT-TNFSF14	0.0147	0.0656	35.6%
CX3CL1	0.0147	0.0656	18.5%
CXCL6	0.0153	0.0656	82.4%
CXCL9-MIG	0.0165	0.0656	39.7%
SIRT2	0.0173	0.0656	44.9%
IL-10-R-beta	0.0179	0.0656	19.6%
MCP-1-CCL2	0.0191	0.0656	36.2%
HGF	0.0195	0.0656	37.9%
Eotaxin-1	0.0198	0.0656	31.3%
AXIN1	0.021	0.0656	11.2%
CCL19	0.0217	0.0656	44.0%
CDCP1	0.0223	0.0656	26.7%
CD40	0.0233	0.0656	18.8%
IL-8	0.0238	0.0656	47.5%
SULT1A1	0.0256	0.0656	21.0%
Beta-NGF	0.0286	0.0679	11.8%
OSM	0.0298	0.0685	78.7%
CCL20	0.0298	0.0685	43.7%
TWEAK-TNFSF12	0.0316	0.0687	21.7%
EIF4EBP1	0.0339	0.0716	59.2%
MIP-1-alpha-CCL3	0.0384	0.0788	16.1%
CXCL11	0.0384	0.0788	54.6%
IL12B	0.0386	0.0788	28.9%
IL18R1	0.0436	0.0828	20.8%
CXCL1	0.0459	0.0852	52.8%		FDR < 0.10