Ethanol-Induced Alterations of T Cells and Cytokines after Surgery in a Murine Infection Model

Figure 3

Analysis of colony forming units (CFUs) of Klebsiella pneumoniae in a murine model of ethanol exposition for 2 weeks, surgery, and pulmonary infection. (a) Colony forming units (CFU x/g lung tissue × 10⁶) in the lung of animals in ethanol-treated (ETOH) and saline-treated controls (NaCl) at 24 hours or 48 hours after pulmonary infection. when comparing 24 hours to 48 hours (time-dependent effects); when comparing ethanol treatment and saline-controls at the same time-point (ethanol-dependent effects); data are presented as mean ± SEM, Mann–Whitney U test ( each group). (b) Colony forming units (CFU x/ml blood × 10²) in the blood of animals in ethanol-treated (ETOH) and saline-treated controls (NaCl) at 24 hours or 48 hours after pulmonary infection. when comparing 24 hours to 48 hours (time-dependent effects); when comparing ethanol treatment and saline-controls at same time-point (ethanol-dependent effects); data are presented as mean ± SEM, Mann–Whitney U test ( each group). CFU: colony forming unit; ETOH: ethanol treatment; NaCl: saline-treated control; K. pneumoniae: Klebsiella pneumoniae.

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