Research Article

Impaired mRNA Expression of the Migration Related Chemokine Receptor CXCR4 in Mesenchymal Stem Cells of COPD Patients

Table 3

Lung function test results.

COPD patients ()Controls () value

FEV1%49 (35–72)107 (80–120)<0.001
FVC%64 (56–81)103 (87–120)0.001
FEV1/FVC ratio60 (45–70)79 (75–83)<0.001
RV%165 (141–204)105 (79–139)0.045
TLC%112 (99–123)98 (94–112)NS
RV/TLC ratio56 (50–69)37 (28–45)0.001
DLCO%65 (27–94)82 (72–96)NS
KCO%84 (43–110)90 (77–106)NS

Values are expressed as median (interquartile range); value < 0.05 as statistically significant; FEV1 = forced expiratory volume in 1 second; FVC = forced vital capacity; TLCOc = transfer factor of the lung for carbon monoxide; KCO = transfer coefficient; RV = residual volume; TLC = total lung capacity.