Therapeutic Effects of the Combination of Alpha-Lipoic Acid (ALA) and Coenzyme Q10 (CoQ10) on Cisplatin-Induced Nephrotoxicity

Figure 2

Creatinine clearance in the studied groups. Creatinine clearance was significantly reduced when group II was compared to other groups. value was 0.00081. Combination therapy resulted in a significant elevation of creatinine clearance when compared to monotherapy (i.e., group V compared to group III and group IV). value was 0.0176.