Inflammatory Serum Biomarkers in Colorectal Cancer in Kazakhstan Population

Table 2

The content of biomarkers in the studied groups.

Serum biomarkers (pg/mL)	Groups (Me[Q1; Q3])				KW value
	Control	G1	G2	G3
SCF	52, 2 [38, 250, 65, 11]	54, 17 [34, 3, 67, 2]	52, 5 [34, 9, 64, 05]	50, 75 [28, 75; 66, 93]	0.77
VEGF	89, 5 [55, 68; 121, 56]	94, 47 [60, 17, 140, 5]	108, 6 [80, 79; 158, 40]	98, 62; [90, 34; 127, 48]	0.07
FGF2	89, 5 [64, 5, 190, 6]	111, 68 [91, 15; 749, 70]	136, 5 [78, 0, 273, 0]	128, 0 [69, 2; 813, 7]	0.024
IL6	2, 13 [0, 00; 7, 39]	6, 8 [6, 6; 12, 30]	9, 05 [2, 9, 13, 06]	7, 73 [5, 9, 10, 5]	0.001
IL8	14, 24 [8, 87, 39, 10]	12, 07 [7, 89; 46, 41]	19, 90 [10, 78; 41, 46]	20, 49 [5, 4, 61, 04]	0.55
MIF	401, 7 [211, 2, 728, 0]	116, 7 [83, 8, 317, 9]	215, 8 [131, 8, 424, 3]	195, 3 [111, 5, 361, 2]	0.001
SFAS	1870, 5 [1355, 7, 2427, 4]	1672, 4 [1453, 9, 3165, 4]	2037, 1 [1547, 2, 2857, 2]	1483, 3 [1394, 1, 1696, 4]	0.015
sFASL	42, 14 [25, 4; 59, 78]	46, 58 [16, 1; 67, 51]	54, 54 [29, 29, 76, 16]	54, 54 [39, 39; 61, 81]	0.23
TGF	9, 8 [5, 0, 15, 01]	6, 23 [2, 62, 14, 02]	9, 7 [4, 32; 14, 70]	8, 15 [5, 21; 11, 92]	0.42
TNF	6, 10 [4, 31; 8, 71]	7, 79 [5, 52; 8, 89]	8, 5 [5, 73; 12, 35]	8, 3 [6, 86; 10, 35]	0.0028
TRAIL	108, 94 [73, 45; 143, 73]	113, 75 [50, 25;157, 99]	102, 6 [65, 75; 139, 62]	79, 72 [50, 37; 109, 28]	0.13
PDL1	10, 25 [7, 12, 40, 4]	30, 36 [1, 4; 38, 46]	33, 14 [3, 5, 44, 0]	35, 42 [20, 9; 46, 39]	0.003

Notes: KW: Kruskal–Wallis test value. Values in bold indicate significant difference at  < 0.05.