Research Article
Influence of Pathogen Type on Neonatal Sepsis Biomarkers
Table 3
The main indicators of leukocytes and platelets.
| | Parameter | Control | Gram-positive bacteremia | Gram-negative bacteremia | P value |
| | Leukocytosis (109 cells/l), Me (Q1; Q3) | 18.3 (14.4; 20.7) | 13.3 (12.3; 15.1) | 15.3 (8.8; 25.2) | >0.05 | | Leukopenia less than 109 cells/l | 1/20 (5%) | 1/16 (6.25%) | 1/10 (10%) | >0.05 | | Leukocytosis more than 109 cells/l | 7/20 (35%) | 3/16 (18.75%) | 3/10 (30%) | >0.05 | | Lymphocytes (%), Me (Q1; Q3) | 52.0 (44.9; 68.0) | 40.0 (32.3; 51.1) | 49.3 (35.6; 54.1) | 0.03 | | Neutrophils (%), Me (Q1; Q3) | 29.0 (19.2; 40.8) | 47.1(37.5; 57.1) | 39.5 (34.4; 43.2) | 0.003 | | Lymphocytes (109 cells/l), Me (Q1; Q3) | 10.0 (7.2; 13.1) | 5.0 (3.5; 6.7) | 6.4 (3.1; 14.3) | 0.02 | | Neutrophils (109 cells/l), Me (Q1; Q3) | 4.55 (3.1; 6.3) | 6.0 (4.0; 8.8) | 4.9 (2.43; 10.0) | >0.05 | | NLR, Me (Q1; Q3) | 0.56 (0.27; 0.80) | 1.39 (0.72; 1.52) | 0.82 (0.63; 1.3) | 0.006 | | NLR>1 (count/all) | 1/20 (5.0%) | 9/16 (56.3%) | 4/10 (40%) | 0.004 | | DOR (±95% CI) | | 24.4 (2.6; 229) | 12.6 (1.17; 136) | | | Sensitivity, % | | 52.6 | 40 | | | Specificity, % | | 95 | 95 | | | Positive predictive value (PPV), % | | 90.0 | 80 | | | Negative predictive value (NPV), % | | 73.0 | 76 | | | Platelets (109 cells/l), Me (Q1; Q3) | 151.0 (131.0; 167.0) | 116.0 (50.0; 176.0) | 154 (47.0; 176.0) | >0.05 | | PLR, Me (Q1; Q3) | 16.62 (10.1; 19.8) | 25.9 (12.4; 39.1) | 12.4 (10.1; 12.56) | >0.05 | | Platelets less 50 109 cells/l (count/all) | 1/20 (5%) | 6/16 (37.5%) | 4/10 (40.0%) | 0.031 | | DOR (±95% CI) | | 11.4 (1.2; 108) | 12.6 (1.1; 136) | | | Sensitivity, % | | 37.5 | 40 | | | Specificity, % | | 95 | 95 | | | Positive predictive value (PPV), % | | 85.7 | 80 | | | Negative predictive value (NPV), % | | 62.5 | 76 | | | Statistically significant p values are in bold. | | P value, Kruskal–Wallis test for comparing 3 groups. |
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