Research Article

Phase I/II Clinical Trial of Autologous Activated Platelet-Rich Plasma (aaPRP) in the Treatment of Severe Coronavirus Disease 2019 (COVID-19) Patients

Table 3

Primary outcomes of the patients.

OutcomesaaPRP treatment

Hospitalization
 Median duration of all patients from initial hospitalization in emergency room to ward room, days4 (1 to 8)
 Median duration of all patients in ICU, days9 (5 to 16)
 Median duration of among patients from emergency room and ward room to ICU who recovered, days17 (10 to 23)

Oxygen
 No. of patients/total no. (%)10/10 (100)
 Type of oxygen support, no./total no. (%)
  NRM2/10 (20)
  HFNC5/10 (50)
  Ventilator3/10 (30)
 Median days receiving oxygen–days
  NRM5 (4 to 6)
  HFNC9 (7 to 14)
  Ventilator6 (3 to 6)

Recovery
 No. of recoveries, %9/10 (90)
 Median time to recovery, days9 (5 to 16)

Mortality
 No of deaths, %1/10 (10)
 Median time to passed away, days8

Main cause of mortality
 Heart failure, %1/1 (100)