Associations between Hypertriglyceridemia and Circulating Neutrophil Subpopulation in Patients with Dyslipidemia

Table 1

Clinical and laboratory characteristics of patients.

Characteristics	NormoTG (n = 69)	HyperTG (n = 22)	Overall (n = 91)
Male, n (%)/female, n (%)	34 (49.3)/35 (50.7)	12 (54.5)/10 (45.5)	46 (50.5)/45 (49.5)	0.596
Age, years, Ме (LQ; UQ)	49.0 (44.0; 52.5)	54.5 (49.0; 58.7)	50.0 (45.0; 57.0)	0.031
BMI, kg/m^2, Ме (LQ; UQ)	26.9 (24.8; 30.2)	29.7 (25.9; 32.3)	27.4 (25.2; 31.2)	0.048
Obesity, n (%)	18 (26.1)	10 (45.5)	28 (30.7)	0.055
Abdominal obesity, n (%)	39 (56.5)	16 (72.7)	55 (60.4)	0.087
Smoking, n (%)	16 (23.2)	5 (22.7)	21 (23.1)	0.608
T2DM, n (%)	4 (5.79)	2 (9.09)	6 (6.59)	0.429
Hypertension, n (%)	34 (49.3)	13 (59.1)	47 (51.6)	0.294
Βeta-blockers, n (%)	14 (20.3)	7 (31.8)	21 (23.1)	0.291
Renin-angiotensin system inhibitors, n (%)	15 (21.7)	9 (40.9)	24 (26.4)	0.094
Diuretics, n (%)	6 (8.69)	3 (13.6)	9 (9.89)	0.392
Statins, n (%)	19 (27.5)	9 (40.9)	28 (30.7)	0.242
Leukocytes, cells × 10^9/l, Ме (LQ; UQ)	5.40 (4.70; 6.40)	6.50 (5.75; 7.30)	5.70 (4.75; 6.65)	0.008
Neutrophils, cells × 10^9/l, Ме (LQ; UQ)	3.10 (2.70; 3.90)	4.00 (3.43; 4.38)	3.50 (2.90; 4.20)	0.029
Lymphocytes, cells × 10^9/l, Ме (LQ; UQ)	1.60 (0.99; 2.10)	1.35 (1.20; 2.30)	1.50 (1.10; 2.10)	0.513
NLR, Ме (LQ; UQ)	2.08 (1.46; 3.05)	2.68 (1.71; 3.42)	2.14 (1.48; 3.50)	0.672
TC, mmol/l, Ме (LQ; UQ)	5.76 (5.01; 6.48)	6.32 (5.24; 7.17)	5.81 (5.11; 6.51)	0.134
LDL-C, mmol/l, Ме (LQ; UQ)	3.88 (3.00; 4.53)	3.34 (2.90; 4.19)	3.43 (2.90; 4.25)	0.304
HDL-C, mmol/l, Ме (LQ; UQ)	1.46 (1.20; 1.64)	1.23 (1.17; 1.38)	1.38 (1.18; 1.61)	0.061
TG, mmol/l, Ме (LQ; UQ)	1.10 (0.75; 1.40)	2.07 (1.90; 3.21)	1.35 (0.99; 1.80)	<0.0001
Non-HDL-C, mmol/l, Ме (LQ; UQ)	4.09 (3.42; 4.98)	4,93 (3.95; 5.94)	4.25 (3.59; 5.23)	0.030
Glycated haemoglobin, %, Ме (LQ; UQ)	5.60 (5.22; 6.03)	5.80 (5.35; 6.06)	5.67 (5.22; 6.05)	0.305
eGFR, ml/min/1.73 m^2, Ме (LQ; UQ)	74.0 (62.7; 98.0)	67.5 (54.2; 84.7)	72.0 (61.0; 93.4)	0.076

NormoTG = normotriglyceridemia; HyperTG = hypertriglyceridemia; BMI = body mass index; TC = total cholesterol; HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol; Non-HDL-C = non-high-density lipoprotein cholesterol; eGFR = estimated glomerular filtration rate; T2DM = type 2 diabetes mellitus; NLR = neutrophil-to-lymphocyte ratio; Me = median; LQ = lower quartile; UQ = upper quartile.