Osteoarthritis Affects Mammalian Oogenesis: Effects of Collagenase-Induced Osteoarthritis on Oocyte Cytoskeleton in a Mouse Model

Figure 1

Meiotic spindle length. (a, b) Data for M I and (c, d) data for M II. (a) M I mean spindle length (total mean ± 1 SD), comparison of controls (26.26 ± 7.52 μm, n = 86) and CIOA (37.59 ± 5.63 μm, n = 139); independent samples t-test, . (b) Distribution of M I spindle length categories in %. “Normal” range (mean ± 1 SD) from the control group. Control group (n = 86): short (n = 13), normal (26.26 ± 7.52 μm, n = 60), long (n = 13); CIOA (n = 139): normal (26.26 ± 7.52 μm, n = 50), long (n = 89); Fisher–Freeman–Halton Exact Test, . (c) M II mean spindle length (total mean ± 1 SD), comparison of controls (24.72 ± 7.46 μm, n = 116) and CIOA (37.04 ± 6.38 μm, n = 51); independent samples t-test, . (d) Distribution of M II spindle length category in %. “Normal” range (mean ± 1 SD) from the control group. Control group (n = 116): short (n = 8) < normal (24.72 ± 7.46 μm, n = 94) < long (n = 14); CIOA (n = 51): normal (24.72 ± 7.46 μm, n = 18) < long (n = 33); Fisher–Freeman–Halton Exact Test, .

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