Osteoarthritis Affects Mammalian Oogenesis: Effects of Collagenase-Induced Osteoarthritis on Oocyte Cytoskeleton in a Mouse Model

Figure 3

Spindle poles width. (a, b) data for M I and (c, d) data for M II. (a) M I mean pole width of the spindles. Spindle poles width (total mean ± 1 SD) of the control group (3.60 ± 1.90 μm, n = 172) and CIOA (7.00 ± 2.78 μm, n = 278); independent samples t-test, . (b) Distribution of M I pole width category frequencies in %. “Normal” range (mean ± 1 SD) from the control group. Control group (n = 172): narrow (n = 19), normal (3.60 ± 1.90 μm, n = 135), and broad (n = 18); CIOA (n = 278): narrow (n = 2), normal (3.60 ± 1.90 μm, n = 75), and broad (n = 201); Fisher–Freeman–Halton Exact Test, . (c) M II mean pole width of the spindles. Spindle poles width (total mean ± 1 SD) of the control group (3.56 ± 1.97 μm, n = 232) and CIOA (6.81 ± 2.67 μm, n = 102); independent samples t-test, . (d) Distribution of M II pole width category frequencies in %. “Normal” range (mean ± 1 SD) from the control group. Control group (n = 232): narrow (n = 42), normal (3.56 ± 1.97 μm, n = 150), and broad (n = 40); CIOA (n = 102): normal (3.56 ± 1.97 μm, n = 38) and broad (n = 64). Fisher–Freeman–Halton Exact Test, .

(a)

(b)

(c)

(d)