Extensive Study on Hematological, Immunological, Inflammatory Markers, and Biochemical Profile to Identify the Risk Factors in COVID-19 Patients
Table 3
Comparative analysis of immunological, inflammatory markers, and hematological and clinical biochemical characteristics between two groups of total severe patients with and without O2 requirement.
Parameter
Total COVID-19 patients (No. = 88)
Severe patients (pneumonia with O2 requirement)
Severe patients (pneumonia without O2 requirement)
No of patients
54 (61%)
34 (39%)
—
Sex, F/M
14/40
14/20
0.02
Age (years)
43.6±8.82
45.70±13.09
NS
Range
(34–72)
(34–68)
WBC (109/L)
14.51±5.70
12.15±4.86
0.04
Lym (109/L)
0.544±0.02
1.72±0.11
0.0001
Neu (109/L)
12.27±0.82
9.86±0.69
0.04
Mon (109/L)
0.59±0.04
0.97±0.07
0.0001
RBC (1012/L)
3.93±0.6
4.59±1.1
NS
Hb (g/dl)
10.94±2.59
11.15±1.43
NS
ESR (mm/h)
55.59±14.19
44.11±11.85
0.03
Hs-CRP (mg/L)
46.29±5.71
37.70±3.23
0.009
IL-6 (pg/ml)
911.97±40.94
271.19±16.75
0.0001
LDH (U/L)
713.50±51.53
607.11±45.79
NS
Ferritin (ng/ml)
1010.64±101.96
976.29±95.93
NS
ALT (U/L)
35.84±5.34
28.51±3.61
0.02
AST (U/L)
35.48±2.29
40.20±4.10
NS
Creatinine (mg/dl)
1.45±0.37
0.740±0.07
0.01
Urea (mg/dl)
76.85±7.41
48.20±4.75
0.006
Albumin (g/dl)
3.40±0.50
3.33±0.41
NS
Direct bilirubin (mg/dl)
0.18±0.01
0.20±0.03
NS
Total bilirubin (mg/dl)
0.67±0.04
0.55±0.05
NS
Glucose (g/dl)
241.49±16.27
178.36±18.29
0.01
D-dimer (ng/ml)
2.13±0.07
3.51±0.70
0.01
APTT (sec)
29.0±9.22
27.41±1.70
NS
Troponin T (ng/ml)
Negative
Negative
denotes statistical significance at the 0.05 level. Data are presented as mean ± standard deviation (range).
