Nanoparticle Enhanced MRI Scanning to Detect Cellular Inflammation in Experimental Chronic Renal Allograft Rejection

Figure 3

(a) F4/80 staining (top panel) for monocyte derived macrophages in the spleen and allograft and isograft (hollow arrows). Prussian blue staining (bottom panel) comparing iron deposition in the spleen, allograft tissue, and isograft (sold black arrows). (b) Histological monocyte count in allograft, isograft, and nontransplanted native kidneys. (c) Electron microscopy of macrophages in renal allograft tissue. The inlay (top right, magnification from black box) demonstrates USPIO within lysosomes.

(a)

(b)

(c)