fdgpet wide use diagnos cardiac inflamm cardiac sarcoidosi physiolog myocardi fdg uptak often creat problem when assess possibl patholog glucos metabol heart sever factor fast blood glucos hormon level influenc normal myocardi glucos metabol the effect outdoor temperatur myocardi fdg uptak has been report befor retrospect review 29 cancer patient who underw pet scan warm summer month again cold winter month obtain myocardi liver mediastin standard uptak valu suvs well quantit cardiac heterogen myocardi fdg uptak pattern also compar age bodi mass index other variabl the mean myocardi fdg uptak show signific differ between summer winter month averag outdoor temperatur did correl signific myocardi suvmax either summer winter the heterogen myocardi fdg uptak did differ signific between season outdoor temperatur seem have signific effect myocardi fdg uptak heterogen therefor warm patient prior attend cardiac pet studi order reduc physiolog myocardi fdg uptak seem unnecessari

Jukka Schildt

Antti Loimaala

Eero Hippeläinen

Päivi Nikkinen

Aapo Ahonen

Seasonal Temperature Changes Do Not Affect Cardiac Glucose Metabolism

background intraoper imag can identifi cancer cell order improv resect thus fluoresc contrast agent have emerg our object preclin comparison two fluoresc dye ec17 otl38 which both target folat receptor have differ fluorochrom materi hela cell line were use vitro vivo comparison ec17 otl38 bright sensit pharmacokinet biodistribut vivo experi were perform mice result the peak excit emiss wavelength ec17 otl38 were 470520 774794 respect vitro otl38 requir increas incub time compar ec17 maximum fluoresc howev peak signaltobackground ratio sbr 14fold higher compar ec17 within 60 minut addition sbr detect smaller quantiti cell improv otl38 vivo mean improv sbr tumor visual use otl38 compar ec17 33 fold rang 148543 neither dye caus notic toxic anim studi conclus preclin test otl38 appear have superior sensit bright compar ec17 this coincid accept belief near infrar nir dye tend have less autofluoresc scatter issu than visibl wavelength fluorochrom

Elizabeth De Jesus

Jane J. Keating

Sumith A. Kularatne

Jack Jiang

Ryan Judy

Jarrod Predina

Shuming Nie

Philip Low

Sunil Singhal

Comparison of Folate Receptor Targeted Optical Contrast Agents for Intraoperative Molecular Imaging

multimod imag provid coregist petct spectct imag howev multimod workflow usual consist sequenti scan from individu imag compon each modal this typic workflow may result long scan time limit throughput imag system convers acquir multimod data simultan may improv correl registr imag improv tempor align acquir data increas imag throughput benefit scan subject minim time under anesthet work demonstr feasibl procedur modifi commerci avail preclin spectct platform enabl simultan spectct acquisit also evalu perform simultan spectct tomograph imag modifi system perform access use 57 sourc imag qualiti evalu phantom seri simultan spectct scan

Dustin R. Osborne

Derek W. Austin

Feasibility and Initial Performance of Simultaneous SPECT-CT Imaging Using a Commercial Multi-Modality Preclinical Imaging System

objectiv investig whether ultrasmal paramagnet particl iron oxid uspio enhanc magnet reson imag mri can detect experiment chronic allograft damag murin renal allograft model materi method two cohort mice underw renal transplant either syngen isograft allograft kidney mri scan perform prior 48 hour after uspio infus use weight protocol valu were calcul indic degre uspio uptak nativ kidney skelet muscl were imag refer tissu renal explant analys histolog electron microscopi result valu allograft group were higher compar isograft group when index nativ kidney median 124 interquartil rang 112 136 versus 096 092 104 valu were also higher allograft transplant when index skelet muscl 624 563 1351 compar nativ kidney 291 111 646 increas signal kidney allograft associ macrophag iron stain histolog uspio were identifi within tissu resid macrophag electron microscopi conclus uspioenhanc mri identifi macrophag

S. R. Alam

G. H. Tse

C. Stirrat

T. J. MacGillivray

R. J. Lennen

M. A. Jansen

D. E. Newby

L. Marson

P. A. Henriksen

Nanoparticle Enhanced MRI Scanning to Detect Cellular Inflammation in Experimental Chronic Renal Allograft Rejection

objectiv studi compar outcom singl cmethoxyisobutylisonitril csestamibi dualtrac csestamibi scintigraphi combin 123 befor primari surgeri primari hyperparathyroid phpt scarc method compar csestamibi 123 csestamibi singlecentr retrospect seri 269 phpt patient the result were relat laboratori surgic histolog find result csestamibi 123 csestamibi were posit 206 766 111 413 269 patient respect 0001 accuraci csestamibi 123 csestamibi were 634 349 respect 96 0001 preval multiglandular diseas 152 multiglandular diseas csestamibi 123 csestamibi reveal 438 221 patholog gland respect 0001 cure rate similar patient 191206 927 without 59 63 937 posit csestamibi 123 find durat target surgeri one two quadrant 21 15 minut shorter than bilater neck explor respect both 0001 higher serum calcium 0014 pth 0055 concentr larger tumour 0001 character 206 patient posit preoper scan who were cure remov singl adenoma conclus csestamibi 123 scintigraphi more accur than csestamibi befor surgeri phpt howev outcom surgeri determin scintigraphi alon

Eeva M. Ryhänen

Ilkka Heiskanen

Mika Väisänen

Eliisa Löyttyniemi

Camilla Schalin-Jäntti

Matti J. Välimäki

99mTechnetium Sestamibi-123Iodine Scintigraphy Is More Accurate Than 99mTechnetium Sestamibi Alone before Surgery for Primary Hyperparathyroidism

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International Journal of Molecular Imaging

International Journal of Molecular Imaging