Research Article

Lactobacillus rhamnosus GG Suppresses Meningitic E. coli K1 Penetration across Human Intestinal Epithelial Cells In Vitro and Protects Neonatal Rats against Experimental Hematogenous Meningitis

Figure 2

Effects of LGG on E. coli K1 translocation across Caco-2 monolayers (a) and transepithelial electrical resistance (TEER) of Caco-2 monolayers (b). (a) Epithelial cells were incubated with various doses of L. rhamnosus for 3 hours before adding 107 E44. Transcytosis assays were carried out as described above. All values represent the means of triplicate determinations at 4 hours. Experiments were repeated three times. Error bars indicate standard deviations. 𝑃 < . 0 5 . (b) TEER was not significantly altered after 0 to 6 hours incubation.
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(a)
647862.fig.002b
(b)