Epithelial Cell Gene Expression Induced by Intracellular Staphylococcus aureus

Table 3

Validation of selected genes by QRT-PCR.

Category	Gene	Fold change (P value)
		2 h	4 h	6 h	8 h
Stress response	atf3	15.45 (.001)	4.46 (.005)	1.38 (.004)	1.97 (.027)
	c-fos	4.55 (.001)	1.32 (.005)	1.47 (.001)	1.86 (.001)
	c-jun	2.93 (.001)	1.26 (.001)	1.77 (.001)	2.91 (.001)
	junb	3.60 (.001)	1.26 (.001)	1.37 (.008)	2.29 (.004)
	sgk	3.36 (.001)	1.20 (.001)	1.87 (.001)	2.02 (.001)
Signal transduction	arhb	2.61 (.002)	1.80 (.001)	2.17 (.001)	1.71 (.019)
	map2k3	1.57 (.001)	1.89 (.013)	2.04 (.005)	2.12 (.001)
Proinflammatory response	il1b	3.64 (.001)	1.58 (.007)	2.02 (.001)	1.47 (.002)
	tnfa	3.36 (.001)	1.30 (.009)	2.21 (.001)	1.43 (.001)
	il6	2.65 (.001)	1.87 (.001)	2.96 (.001)	1.55 (.004)
	ccl20	6.29 (.001)	5.07 (.002)	4.53 (.001)	1.82 (.001)
	cxcl1	3.82 (.001)	2.41 (.001)	2.87 (.001)	3.05 (.050)
	cox2	4.16 (.001)	3.69 (.001)	3.96 (.001)	2.95 (.011)
Cell proliferation and Proapoptosis	dkk1	3.43 (.001)	6.90 (.001)	4.31 (.001)	2.28 (.001)
	igfbp1	3.50 (.001)	6.82 (.045)	4.20 (.010)	9.89 (.001)
	casp9	2.74 (.001)	1.34 (.005)	1.42 (.004)	1.13 (.021)
Profibrotic	tgfb1	1.55 (.002)	1.20 (.023)	1.71 (.001)	2.66 (.001)
	thbs1	1.83 (.001)	4.55 (.001)	4.12 (.002)	4.09 (.001)
	cyr61	3.31 (.001)	4.01 (.002)	2.28 (.016)	2.44 (.001)
Cholesterol synthesis	hmgcr	1.25 (.025)	0.17 (.001)	0.15 (.001)	0.17 (.001)
	sqle	1.00 (.005)	0.30 (.001)	0.14 (.001)	0.15 (.001)
	dhcr7	1.17 (.050)	0.50 (.001)	0.27 (.001)	0.16 (.001)
	ldlr	1.57 (.010)	0.09 (.001)	0.12 (.001)	0.23 (.001)