Differential Adaptations of Methicillin-Resistant Staphylococcus aureus to Serial In Vitro Passage in Daptomycin: Evolution of Daptomycin Resistance and Role of Membrane Carotenoid Content and Fluidity

Table 2

In vitro susceptibility profiles to host defense peptides (HDPs).

Strains	hNP-1 (10 μg/mL)	hNP-1 (20 μg/mL)
CB1118	25 ± 14	12 ± 13
CB2206	20 ± 12	9 ± 9
CB2207	46 ± 13^*+	15 ± 7
CB2208	68 ± 10^*	55 ± 32^*+
CB2209	102 ± 19^*	101 ± 26^*
CB2210	99 ± 16^*	94 ± 15^*

^*P value < 0.05 versus parental strain; ^*+P value < 0.08 versus parental strain.