Review Article
Application of Bioluminescence Imaging for In Vivo Monitoring of Fungal Infections
Table 1
Key features of selected luciferases from different phylogenetic origins.
| | Luciferase origin | Organism (family) | Substrate | Cosubstrate | Composition (mass) | Localisation (native) | Peak emission (nm) |
| | Vibrio spec. | Bacteria (Vibrionaceae) | Long-chain aliphatic aldehyde | O2; FMNH2 | heterodimer (77 kDa) | Cytoplasm | 490 |
| | Photorhabdus spec. | Bacteria
(Enterobacteriaceae) | Long-chain aliphatic aldehyde | O2; FMNH2 | heterodimer (77 kDa) | Cytoplasm | 490 |
| | Photinus pyralis | Firefly
(Lampyridae) | Benzothiazoyl-thiazole | O2; ATP | monomer (62 kDa) | Peroxisome | 561–578* |
| | Pyrophorus plagiophthalamus | Click beetle (Elateridae) | Benzothiazoyl-thiazole | O2; ATP | monomer (62 kDa) | Peroxisome | 548–594 |
| | Renilla reniformis | Sea pansy (Renillidae) | Benzylimidazo-pyrazinone coelenterazine | O2 | monomer (35 kDa) | Cytoplasm | 480 |
| | Gaussia princeps | Copepod (Metridinidae) | Benzylimidazo-pyrazinone coelenterazine | O2 | monomer (19 kDa) | Secreted | 480 |
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*Peak emission is temperature sensitive and gradually shifts to 612 nm at 37°C [22].
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