Research Article
The In Vitro Antibiotic Susceptibility of Malaysian Isolates of Burkholderia pseudomallei
Table 2
The MIC of antibiotics against 170 Burkholderia pseudomallei isolates.
| | Antibiotic | No. of isolates with the MIC (µg/mL) of | MIC (µg/mL) | %S | | ≤0.25 | 0.38 | 0.5 | 0.75 | 1.0 | 1.5 | 2.0 | 3.0 | 4.0 | 6.0 | 8.0 | 12.0 | 16 | 128 | ≥256 | MIC50 | MIC90 |
| | AMC | | | | | | 39 | 118 | 9 | 3 | | | | | | 1 | 2.0 | 3.0 | 99.4 | | CAZ | | | | 1 | 11 | 75 | 65 | 15 | 2 | | | | | | 1 | 1.5 | 2.0 | 99.4 | | CIP | | | 7 | 23 | 42 | 56 | 28 | 10 | | 2 | | 1 | | | 1 | 1.5 | 2.0 | 42.3 | | CHL | | | | | | | 1 | 14 | 37 | 81 | 31 | 4 | 1 | 1 | | 6.0 | 8.0 | 96.5 | | SXT | 18 | 14 | 19 | 16 | 28 | 24 | 34 | 10 | 5 | 2 | | | | | | 1.0 | 2.0 | 90 | | DOX | 1 | 10 | 11 | 26 | 48 | 48 | 20 | 4 | 1 | | 1 | | | | | 1.0 | 2.0 | 99.4 | | IMI | 48 | 114 | 7 | | | | | | | 1 | | | | | | 0.38 | 0.38 | 99.4 | | MEM | | 2 | 12 | 98 | 49 | 8 | 1 | | | | | | | | | 0.75 | 1.0 | 100 | | TZP | | | 2 | | 50 | 99 | 16 | 1 | 2 | | | | | | | 1.5 | 2.0 | 100 | | SAM | | | | | | 1 | 47 | 99 | 20 | 1 | 1 | | | | 1 | 3.0 | 4.0 | 99.4 | | TIG | | 5 | 15 | 6 | 13 | 32 | 39 | 36 | 19 | 4 | 1 | | | | | 1.5 | 4.0 | 64.7 |
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AMC: amoxicillin/clavulanic acid; CAZ: ceftazidime; CIP: ciprofloxacin; CHL: chloramphenicol; SXT: trimethoprim-sulfamethoxazole; DOX: doxycycline; IMI: imipenem; MEM: meropenem; TZP: piperacillin/tazobactam; SAM: ampicillin/sulbactam; TIG: tigecycline.
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