International Journal of Microbiology / 2014 / Article / Tab 1

Review Article

Comparative Analysis of Protein Glycosylation Pathways in Humans and the Fungal Pathogen Candida albicans

Table 1

Human and C. albicans homolog proteins involved in the N-linked glycosylation pathway.

Protein functionProtein Human/Candida Human ID*Candida ID*Id**COV***

Glycosyltransferases
UDP-GlcNAc: Dol-P N-acetylglucosaminephosphotransferaseGT1/Alg7NP_001373.2XP_716028.137%87%
UDP-GlcNAc: Dol-PP-GlcNAc N-acetylglucosaminyl transferaseAlg13NP_001093392.1XP_718987.130%60%
UDP-GlcNAc: Dol-PP-GlcNAc N-acetylglucosaminyl transferaseAlg14NP_659425.1XP_717086.137%77%
GPD-Man: Dol-PP-GlcNAc2   1,4-mannosyltransferaseAlg1NP_061982.3XP_711858.134%88%
GPD-Man: Dol-PP-GlcNAc2Man 1,3- 1,6-mannosyltransferaseAlg2NP_149078.1XP_710581.141%96%
GPD-Man: Dol-PP-GlcNAc2Man3 and Man4   1,2-mannosyltransferaseAlg11NP_001004127.2XP_712508.136%67%
Dol-P-Man: Dol-PP-GlcNAc2Man5   1,3-mannosyltransferase Alg3NP_001006942.1XP_712080.130%81%
Dol-P-Man: Dol-PP-GlcNAc2Man7   1,6-mannosyltransferaseAlg12NP_077010.1XP_716986.133%86%
Dol-PP-Man: Dol-PP-GlcNAc2Man6 and Man8   1,3-mannosyltransferaseAlg9NP_001071158.1XP_713886.136%93%
Dol-PP-Glc: Dol-PP-GlcNAc2Man9   1,3-glucosyltransferaseAlg6NP_037471.2XP_711029.137%87%
Dol-PP-Glc: Dol-PP-GlcNAc2Man9Glc 1,3-glucosyltransferaseAlg8NP_001007028.1XP_721736.141%80%
Dol-PP-Glc: Dol-PP-GlcNAc2Man9Glc2   1,2-glucosyltransferaseAlg10NP_116223.3XP_714677.132%96%
Post flipping chaperone Rft1NP_443091.1XP_717469.127%85%
OST components RBPH1/Ost1NP_002941.1XP_714694.127%85%
DAD1/Ost2NP_001335.1XP_714366.140%81%
N33/Ost3NP_006756.2XP_721902.123%77%
Ost4NP_001128165.1EEQ47486.139%51%
IAP/Ost6NP_115497.4XP_716090.122%84%
RIBIIR/SwpINP_002942.2XP_721287.126%58%
OST48 /Wbp1NP_005207.2XP_713903.124%91%
STT3A/Stt3NP_001265432.1XP_722527.156%94%
STT3BNP_849193.157%
Folding Sensor UGGT1/Kre5NP_064505.1XP_719987.160%57%
Glycosidases
Glucosidase IMOGS/Cwh41NP_001139630.1ABB97046.129%91%
Glucosidase IIGANAB/Rot2NP_938148.1XP_716812.138%98%
GLU2B/Gtb1NP_002734.2 XP_717976.1 39%57%
ER 1,2-mannosidase IMAN1B1/MnsINP_057303.2XP_713641.145%77%

Accession number at NCBI database.
Identity and coverage from BLAST alignment between human and C. albicans homolog sequences, respectively.

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