Review Article
Comparative Analysis of Protein Glycosylation Pathways in Humans and the Fungal Pathogen Candida albicans
Table 4
Human and C. albicans homologous proteins involved in GPI glycosylation.
| | Protein function | Protein H/Ca | Human ID* | Candida ID* | Id** | Cov*** |
| | GlcNAc-PI synthesis | PIG-A/Gpi3 | NP_002632.1 | XP_717439.1 | 49% | 94% | | PIG-C/Gpi2 | NP_714969.1 | XP_717493.1 | 31% | 90% | | PIG-H/Gpi15 | NP_004560.1 | XP_718197.1 | 33% | 44% | | PIG-P/Gpi19 | NP_710149.1 | XP_714916.1 | 33% | 37% | | PIG-Q/Gpi1 | NP_683721.1 | XP_714683.1 | 30% | 42% | | PIG-Y/Eri1 | NP_001036081.1 | XP_715355.1 | 64% | 9% | | GlcNAc-PI de-N-acetylation | PIG-L/Gpi12 | NP_004269.1 | XP_723585.1 | 29% | 55% | | Inositol acylation | PIG-W/Gwt1 | NP_848612.2 | XP_712842.1 | 28% | 99% | | 1,6-mannosyltransferase | PIG-M/Gpi14 | NP_660150.1 | XP_722653.1 | 38% | 94% | | 1,6-mannosyltransferase | PIG-X/Pbn1 | NP_001159776.1 | XP_716695.1 | 19% | 24% | | Etn-P transfer to Man-1 | PIG-N/Mcd4 | NP_789744.1 | XP_716313.1 | 37% | 95% | | 1,6-mannosyltransferase | PIG-V/Gpi18 | NP_060307.2 | XP_713712.1 | 24% | 82% | | 1,2-mannosyltransferase | PIG-B/Gpi10 | NP_004846.4 | XP_721904.1 | 31% | 97% | | Etn-P transfer to Man-3 | PIG-O/Gpi13 | NP_001188413.1 | XP_720956.1 | 38% | 53% | | Etn-P transfer to Man-2 and 3 | PIG-F/Gpi11 | NP_002634.1 | XP_720511 | 35% | 44% | | Etn-P transfer to Man-2 | PIG-G/Gpi7 | NP_001120650.1 | XP_710743.1 | 38% | 47% | | 1,2-mannosyltransferase | Smp3 | NP_079439.2 | XP_715333.1 | 26% | 91% | | Etn-P transfer to Man-2 | Gpi7 | NP_001120650.1 | EEQ42670.1 | 40% | 72% | | GPI transamidase | PIG-K/Gpi8 | NP_005473.1 | XP_711741.1 | 56% | 78% | | | GAA1 | NP_003792.1 | XP_710522.1 | 35% | 49% | | | PIG-S/Gpi17 | NP_149975.1 | XP_716135.1 | 27% | 48% | | | PIG-T/Gpi16 | NP_057021.2 | XP_720200.1 | 29% | 94% | | | PIG-U/Cdc91 | NP_536724.1 | XP_720773.1 | 24% | 92% | | Inositol deacylation | PGAP-1/Bst1 | NP_079265.2 | XP_713657.1 | 31% | 75% | | sn-2 deacylation | PGAP3/Per1 | NP_219487.3 | XP_712020.1 | 26% | 95% | | sn-2 acylation | PGAP2/Cwh43 | NP_001269969.1 | XP_717850.1 | | |
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Accession number at NCBI database.
Identity and coverage from BLAST alignment between human and C. albicans homologous sequences, respectively.
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