Staphylococcus saprophyticus Recovered from Humans, Food, and Recreational Waters in Rio de Janeiro, Brazil

Table 3

Antimicrobial susceptibility and resistance determinants in 98 Staphylococcus saprophyticus isolates.

Antimicrobial agent	Disk diffusion halo (mm)/interpretation	MIC (μg/mL)/interpretation	Resistance determinant
			Gene	Number (%) of isolates
Sulfamethoxazole-trimethoprim	6–12/R	4–64/R	dfrG	15 (15.3)
	6/R	32/R	dfrA	1 (1)
	11/I	8/R	dfrG	1 (1)
	18–35/S	0.125–4/S	dfrG	10 (10.2)
	29–37/S	0.125–2/S	None	71 (72.4)
Erythromycin	6/R	4–≥64/R	erm(C)	7 (7.1)
	6/R	32–>64/R	erm(C), msr(B)	2 (2)
	6/R	>64/R	erm(C), mph(C)	2 (2)
	6/R	≥64/R	msr(A), msr(B)	1 (1)
	6/R	≥64/R	erm(C), msr(A), msr(B)	9 (9.1)
	6–10/R	32–≥64/R	erm(C), msr(A), msr(B), mph(C)	10 (10.2)
	19/I	0.125/S	erm(C)	1 (1)
	22–33/S	0.125–1/S	erm(C)	44 (44.8)
	30/S	1/S	msr(A)	1 (1)
	28–32/S	0.25–1/S	erm(C), msr(A)	7 (7.1)
	28–34/S	1/S	erm(C), msr(B)	3 (3)
	27–30/S	1/S	erm(C), mph(C)	3 (3)
	28–30/S	1/S	erm(C), msr(A), msr(B)	1 (1)
	26–32/S	0.125–1/S	None	7 (7.1)
Clindamycin	30–33/IR^a	0.125–2/S	erm(C)	6 (6.1)
	34/IR^a	0.25/S	erm(C), msr(B)	1 (1)
	28–30/IR^a	0.25/S	erm(C), msr(A), msr(B)	2 (2)
	28–32/IR^a	0.25/S	erm(C), msr(A), msr(B), mph(C)	4 (4)
	25/S	0.25/S	lin(A), erm(C), msr(A), msr(B), mph(C)	1 (1)
	25/S	0.25/S	lin(A), erm(C)	1 (1)
	25–35/S	0.125–0.25/S	None	83 (84.6)
Oxacillin	6–9/R	32–>64/R	mecA	3 (3)
	12/R	1/R	mecA	1 (1)
	20–22/R	0.5–1/R	None	5 (5.1)
	23–35/S	0.5–2/R	None	84 (85.7)
	29–44/S	0.125–0.25/S	None	5 (5.1)
Penicillin	6/R	8–16/R	mecA^b	3 (3)
	15/R	2/R	None	1 (1)
	26–28/R	0.25–1/R	None	2 (2)
	22/R	0.125/S	mecA^b	1 (1)
	17–27/R	0.125/S	None	9 (9.1)
	30–45/S	≤0.125/S	None	82 (83.6)
Gentamicin	14/I	8/I	None	1 (1)
	15/S	8/I	None	1 (1)
	15–37/S	0.125/S	None	96 (97.9)
Norfloxacin	15/I	0.125/S	None	1 (1)
	17–33/S	0.125/S	None	97 (98.9)

The 98 isolates in this table were selected from the 140 obtained to include only one isolate per patient. : macrolide-lincosamide-streptogramin B; R: resistant; I: intermediate resistance; S: susceptible; IR: inducible resistance; MIC: minimum inhibitory concentration. inducible resistance detected in -test. isolates resistant to oxacillin.