|
Reference
(country) | Patients and samples | Reference
Counts | Cutoff
Values | SE/SP/NPV/ER% |
|
Monsen and Rydén 2015
(Turkey) [21] | 4458 urine samples from adults | >104 CFU/mL | 50 BAC/µL
30 WBC/µL | 1/49.7/1/44.8 |
|
García-Coca et al., 2017
(Spain) [22] | 17483 urine samples from 85% women and 14.7% (median age 47 years). 97.4% outpatients and 2.6 hospitalized subjects | >105 CFU/mL | >200 BAC/µL
>40 WBC/µL | AUC (BAC) count:
0.79
AUC (WBC) count:
0.60
ER: 48 |
|
Kulkarni and Nigrin 2013
(Netherlands) [23] | 7322 urinary samples from
60% inpatients and 40% outpatients (average age 66 years) | >105 CFU/mL | >200 BAC/µL | 0.93/0.63/0.96/49 |
|
Íñigo et al.
(2016) [24]
(Spain) | 1934 urine samples: MSU (89.14%), catheterized urine (9.98%), pediatric urine bags (0.72%), suprapubic aspiration (0.16%), belonging to 56% ♀ and 44% ♂ (51.19% hospitalized patients and 48.81% outpatients) | >102 CFU/mL | 460 BAC/µL
40 WBC/µL | 0.98/0.76/0.99/57 |
|
Gessoni et al., 2015
(Italy) [25] | 2335 MSU from adult patients (41% inpatients and 59% outpatients), between 15 to 91 years old (♀: 34%, ♂: 66%) | ≥105 CFU/mL | 175 BAC/µL | 0.95/0.80/—/50 |
|
Martín-Gutiérrez et al., 2015
(Spain) [26] | 346 MSU collected from elderly outpatients with a median age of 76 years (♀: 43%, ♂: 56%) | ≥105 CFU/mL for women
≥104 CFU/mL for men | 200 BAC/µL | 0.99/0.91/0.99/60 |
|
Manoni et al., 2009
(Italy) [27] | 372 MSU specimens from 167 ♂ and 205 ♀ (57.37% outpatients and 42.63% inpatients) | >105 CFU/mL | 14.2 BAC/µL
6.7 WBC/µL
14.2 BAC/µL | 0.8/0.58/0.86/—/—
0.95/0.44/0.95/30.6 |
|
Marschal et al., 2012
(Germany) [28] | 572 urine samples (31.8% catheterized, 65.5% MSU and 2.7% not specified), from 513 patients (27.9% outpatients, 72.1% inpatients) ♀: 48.9% and ♂: 51.1% (mean age of 54.2 years) | >102 CFU/mL | >30 BAC/µL
>20 WBC/µL | 0.80/0.78/—/— |
|
Gutiérrez-Fernández et al., 2012
(Spain) [29] | 1225 urine samples (urine catheter, MSU or pediatric bags) from 158 inpatients (27 catheterized adults, 33 children, 98 inmunocompromised adults) and 1067 outpatients (464 adults and 603 pregnant women). | >105 CFU/mL | 690 BAC/µL
38 WBC/µL | 0.92/0.65/0.97/— |
|
Broeren et al.
(2011) (Netherlands)
[14] | 1577 urine samples collected from 681 outpatients (196 ♂) and 896 (403 ♂) from hospitalized patients | <105 CFU/mL
<104 CFU/mL | 230 BAC/µL
39 BAC/µL | 0.96/0.78/0.99/52
0.82/0.83/0.95/28 |
|
Kadkhoda et al. 2011
(Canada) [30] | 2496 (75%) MSU and 25% catheterized urine (patients origin not informed) | ≥104 CFU/mL
of up two uropathogens
≥105 CFU/mL
Non uropathogens | 20 BAC/µL | 0.93/0.69/—/35 |
|
Pieretti et al. 2010
(Italy) [31] | 703 MSU from 18.2% hospitalized patients and 81.8% outpatients (70.6% females and 29.4% males) | >104 CFU/mL | 65 BAC/µL
100 WCB/µL | 0.98/0.62/0.98/43 |
|
van der Zwet et al. 2010
(Dutch) [32] | 358 urine samples (patients origin not informed) | >104 CFU/mL | 50 BAC/µL
20 WBC/µL | 1/0.8/0.59/42 |
|
De Rosa et al. 2010
(Italy) [33] | 1349 urine samples (patients origin not informed) | >104 CFU/mL for adult
>106 CFU/mL for children. | 170 BAC/µL
150 WBC/µL | 0.98/0.76/0.99/57 |
|
Shang et al. 2013
(China) [34] | 313 urine samples, belonging inpatients and outpatients | >105 CFU/mL for gram (−)
>104 CFU/mL for gram (+) | 100 BAC/µL
56 WBC/µL | 0.86/0.95/0.94/50 |
|
Hu et al. 2010 [35]
(China) | 308 urine samples from outpatients | >105 CFU/mL for gram (−)
>104 CFU/mL for gram (+) | 160 BAC/µL | 0.81/0.83/0.89/55 |
|
Kouri 2000
(Italy) [36] | 1463 MSU samples from adults | >105 CFU/mL | >125 BAC/µL
>40 WBC/µL | 0.99/0.77/0.98/— |
|
