Research Article
Antistaphylococcal and Antibiotic Resistance Modulatory Activities of Thirteen Cameroonian Edible Plants against Resistant Phenotypes
Table 6
MIC of extracts and ciprofloxacin in the absence (−) and presence (+) of chlorpromazine (CPZ) against selected strains of Staphylococcus aureus.
| | Bacterial strainsa | Samplesb and MIC in µg/mL and fold increase of activity (in parentheses) | | DES | HEL | UGB | UGL | CIP | | − | + | − | + | − | + | − | + | − | + |
| | ATCC 25923 | 512 | 512 (1) | − | − | 512 | 512 (1) | 128 | 1024 (0.13) | 2 | 2 (1) | | MRSA3 | 256 | 256 (1) | 1024 | 1024 (1) | 512 | 512 (1) | − | − | 4 | 4 (1) | | MRSA4 | 512 | 512 (1) | − | − | 256 | 256 (1) | 1024 | 1024 (1) | 2 | 2 (1) | | MRSA6 | 256 | 256 (1) | 512 | 128 (2) | 512 | 512 (1) | 256 | −(0.25) | 2 | 2 (1) | | MRSA8 | 256 | 256 (1) | 1024 | 1024 (1) | 256 | 256 (1) | − | − | 1 | 2 (0.5) | | MRSA9 | 256 | 256 (1) | 1024 | 1024 (1) | 512 | 512 (1) | 256 | −(0.25) | 1 | 2 (0.5) | | MRSA11 | 512 | 512 (1) | 1024 | 1024 (1) | 512 | 512 (1) | 128 | −(<0.13) | 4 | 4 (1) | | MRSA12 | 512 | 512 (1) | − | − | 512 | 512 (1) | − | − | 2 | 2 (1) | | SA01 | 512 | 512 (1) | 1024 | 1024 (1) | 512 | 512 (1) | 512 | 512 (1) | 1 | 1 (1) | | SA07 | 512 | 512 (1) | 1024 | 1024 (1) | 512 | 512 (1) | 1024 | 1024 (1) | 4 | 4 (1) | | SA18 | 512 | 512 (1) | − | − | 1024 | 1024 (1) | − | − | 1 | 1 (1) | | SA88 | 512 | 512 (1) | − | − | 1024 | 1024 (1) | − | − | 4 | 4 (1) | | SA114 | 1024 | 1024 (1) | − | − | 1024 | 1024 (1) | − | − | 1 | 1 (1) | | SA135 | 512 | 512 (1) | − | − | 1024 | 1024 (1) | − | − | 1 | 1 (1) |
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aBacterial strain (SA: Staphylococcus aureus; MRSA: methicillin-resistant Staphylococcus aureus); bsamples (DES: Dacryodes edulis seeds, HEL: Hibiscus esculentus leaves, UGL: Uapaca guineensis leaves, UGB: Uapaca guineensis bark, CIP: ciprofloxacin); CPZ: chlorpromazine at 25 µg/mL; CIP: ciprofloxacin; MIC: minimal inhibitory concentration.
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