Current Progress in the Structural and Biochemical Characterization of Proteins Involved in the Assembly of Lipopolysaccharide

Figure 19

LptDE. (a) Ribbon structure of LptDE complex (PDB: 4Q35) [131]. LptD is colored blue, and LptE is colored red. A C8E detergent molecule is shown bound to the N-terminal β-jellyroll domain of LptD. (b) Periplasmic view of (a). (c) LptE from the LptDE complex in (a). Conserved basic residues shown to be important for LptE binding to LPS are highlighted [135]. (d) Hydrophobicity surface of (b). Hydrophobicity is shown in an orange-blue scale with orange as the hydrophobic end. The ellipse marks the periplasmic entrance to the LptDE lumen.

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