Multidrug-Resistant Hypervirulent Klebsiella pneumoniae Found Persisting Silently in Infant Gut Microbiota
Table 1
Patient data, sample data, and demonstrated drug resistance of the studied K. pneumoniae isolates.
Sample name
Kleb102
Kleb22
Kleb24
Kleb27
Kleb28
Kleb29
Kleb60
Kleb85
Kleb90
Kleb91
Sample number
102
22
24
27
28
29
60
85
90
91
Delivery
C
V
V
V
V
V
C
C
V
C
Patient ID
2
1
3
4
5
6
7
8
1
2
Patient age, days
33
3
3
3
4
3
4
4
90
3
K. pneumoniae,
7
9
8
8
9
8
9
9
8
8
ESBL
-
+
-
-
+
+
+
+
-
+
Klebsiella phage
R
S
R
R
N
R
S
S
R
R
Pyo phage
S
S
S
S
S
S
S
S
S
S
Amikacin
S
S
S
S
S
S
S
S
S
S
Amoxicillin-clavulanic acid
R
R
S
S
R
R
R
R
S
R
Ampicillin
R
R
R
R
R
R
R
R
R
R
Aztreonam
R
R
S
S
R
R
R
R
N
R
Ceftriaxone
R
R
S
S
R
R
R
R
S
R
Chloramphenicol
N
S
S
S
S
S
S
S
S
S
Ciprofloxacin
S
I
S
S
R
I
S
S
S
S
Fosfomycin
R
R
I
R
R
R
R
R
N
R
Gentamicin
S
S
S
N
R
R
S
S
N
S
Imipenem
R
S
S
I
R
I
R
R
N
R
Meropenem
R
S
S
S
S
S
S
S
N
S
Netilmicin
S
R
S
S
R
R
S
S
N
I
Nitrofurantoin
R
I
S
R
R
I
R
R
R
R
Sulfamethoxazole
S
R
S
S
R
R
R
R
N
R
Trimethoprim
S
R
S
S
R
R
R
R
N
R
CFU, colony-forming unit. Delivery: V, vaginal; C, cesarean section. Susceptibility to an antimicrobial agent: S, susceptible, R, resistant; I, intermediate; N, not defined.