Antibacterial and Anticancer Activity and Untargeted Secondary Metabolite Profiling of Crude Bacterial Endophyte Extracts from Crinum macowanii Baker Leaves

Table 4

Antibacterial evaluation of C. macowanii crude leave extract and crude endophyte extracts from the leaves.

Test organism with MIC (mg/mL)
Crude extracts	B. cereus	B. subtilis	S. epidermidis	S. aureus	M. smegmatis	M. marinum	E. aerogenes	E. coli	K. pneumonia	P. vulgaris	P. aeruginosa
T1	2.00	0.500	1.00	0.250	0.500	2.00	8.00	0.250	0.250	0.500	0.125
T2	8.00	1.00	4.00	16.00	1.00	0.500	1.00	0.500	0.500	>16.00	0.250
T3	4.00	4.00	16.00	8.00	0.500	16.00	16.00	8.00	16.00	8.00	16.00
T4	0.500	0.125	0.125	0.500	8.00	0.125	16.00	>16.00	4.00	16.00	8.00
T5	>16.00	2.00	4.00	4.00	8.00	0.500	1.00	2.00	0.500	0.250	1.00
T6	>16.00	4.00	8.00	16.00	4.00	>16.00	16.00	>16.00	>16.00	8.00	1.00
T7	>16.00	0.125	2.00	>16.00	4.00	0.500	16.00	0.250	2.00	4.00	>16.00
T8	4.00	16.00	8.00	2.00	0.500	0.125	8.00	0.500	0.125	16.00	2.00
T9	8.00	0.250	16.00	1.00	0.125	8.00	4.00	1.00	0.500	1.00	0.125
T10	2.00	0.0625	4.00	1.00	16.00	>16.00	1.00	0.500	>16.00	2.00	4.00
Positive control MIC (μg/mL)
T11	0.031	0.031	0.062	0.031	0.062	0.062	0.125	0.125	0.125	0.062	0.031

T1 = C. macowanii leaves, T2 = Raoultella ornithinolytica, T3 = Acinetobacter guillouiae, T4 = Pseudomonas sp., T5 = Pseudomonas palleroniana, T6 = Pseudomonas putida, T7 = Bacillus safensis, T8 = Enterobacter asburiae, T9 = Pseudomonas cichorii, T10 = Arthrobacter pascens, T11 = Positive control streptomycin.