International Journal of Microbiology / 2020 / Article / Tab 5 / Research Article
Antibacterial and Anticancer Activity and Untargeted Secondary Metabolite Profiling of Crude Bacterial Endophyte Extracts from Crinum macowanii Baker Leaves Table 5 LC-Q-TOF-MS analysis of crude extracts of C. macowanii leaves and their bacterial endophytes.
Compound name Rt (min/sec) m /z Molecular formula Reported biological activity Sample Melicopicine 5.64 330.1351 C18 H19 N1 O5 Antiplasmodial activity [94 ] T1 Lycorine 1.92; 13.76; 36.75; 7.23 288.1236 C16 H17 N1 O4 Antibacterial cytotoxic and antitumor activities [95 ] T1, T7, T9, T10 Angustine 10.35; 19.23; 25.98; 11.07 314.1388 C20 H15 N3 O1 Antiproliferative activity [96 ] T1, T7, T9, T10 3-O-methyl epimacowine 5.63 288.1586 C17 H21 NO3 Anticancer [97 ] T7 Crinamidine 17.57; 15.50; 15.44; 6.32 318.1348 C17 H19 N1 O5 Antibacterial [21 ] anticancer activity [98 ] T1, T7, T9, T10 Vasicinol 4.18; 21.69; 21.51; 8.91 205.0977 C11 H12 N2 O2 Antibacterial activity [99 ] T1, T7, T9, T10 Aulicine 1.99 320.1870 C18 H25 NO4 Anticancer activity [97 ] T9 Powelline 19.14, 14.05, 17.98, 7.43 302.1389 C17 H19 N1 O4 Antitumor [100 ] antibacterial [21 ] T1, T7, T9, T10 Brefeldin A 11.52 281.1702 C16 H24 O4 Anticancer [101 ] and antifungal [102 ] T10
Note: T1 = C. macowanii leaves, T7 = Bacillus safensis , T9 = Pseudomonas cichorii , T10 = Arthrobacter pascens .