Spoligotype Diversity of Mycobacterium tuberculosis over Two Decades from Tiruvallur, South India

Figure 3

(a) Phylogenetic tree for the recent survey conducted between 2015 and 2018, showing continuous predominance of the EAI3_IND 11 cluster; it also shows the increase in EAI1_SOM 48 strains in this region. (b) A minimum spanning tree (MST) illustrating the distribution of spoligotypes prevalent in Tiruvallur, South India, from 2001 to 2003. The major spoligotypes are labelled against the cluster depicted by the oval. The pink shadow represents East African Indian lineage, green shadow is for Central Asian (CAS) lineage, and the yellow shadow is for Beijing. The structure of the tree is represented as branches and circles representing each individual pattern The colour of the circle is proportional to the number of clinical isolates in our study, illustrating unique isolates as colourless versus coloured clustered isolates (sky blue ≤ 2, deep blue ≤ 5, navy blue ≤ 10, maroon ≤ 20, and red > 20), and also the size of the circle is proportional to the number of strains in the cluster.

(a)

(b)