Coexistence of Virulence Factors and Efflux Pump Genes in Clinical Isolates of Pseudomonas aeruginosa: Analysis of Biofilm-Forming Strains from Iran

Table 3

Correlation between efflux pumps, biofilm formation, separated clinical isolates, and antibiotic resistance in P. aeruginosa.

Biofilm	Efflux pump families
	RND types			MFS types			SMR types
	MexA	mexB	oprM	oprD	tetA	tetR	emrE
Strong	= 0.009	= 0.001	= 0.008	= 0.009	= 0.039	= 0.022	= 0.041
Moderate	= 0.017	= 0.050	= 0.036	= 0.002	= 0.075	= 0.033	= 0.019
Weak	= 0.043	= 0.003	= 0.032	= 0.017	= 0.015	= 0.048	= 0.028
Clinical isolates
Wound	= 0.040	= 0.029	= 0.016	= 0.048	= 0.066	= 0.043	= 0.051
Urine	= 0.056	= 0.037	= 0.044	= 0.011	= 0.006	= 0.005	= 0.006
Blood	= 0.250	= 0.089	= 0.014	= 0.097	= 0.25	= 0.1	= 0.068
Medical devices	= 0.058	= 0.060	= 0.084	= 0.12	= 0.09	= 0.049	= 0.17
Gender
Male	= 0.31	= 0.11	= 0.33	= 0.47	= 0.075	= 0.082	= 0.059
Female	0.085	0.020	0.009	0.005	0.066	0.043	0.051
Hospital sections
Maternity unit	= 0.049	= 0.016	= 0.055	= 0.005	= 0.009	= 0.045	= 0.043
Pediatrics	= 0.019	= 0.062	= 0.035	= 0.015	= 0.009	= 0.45	= 0.21
Internal unit	= 0.31	= 0.11	= 0.33	= 0.47	= 0.075	= 0.082	= 0.059
Emergency	0.025	0.015	0.084	0.001	0.075	0.033	0.019
ICU	= 0.002	= 0.001	= 0.072	= 0.050	= 0.039	= 0.044	= 0.011
Burns unit	= 0.019	= 0.020	= 0.048	= 0.053	= 0.036	= 0.050	= 0.018
Neurosurgery	= 0.094	= 0.31	= 0.19	= 0.020	= 0.62	= 0. 27	= 0.093