Research Article

Prevalence of Cryptococcal Antigenemia and Associated Factors among HIV/AIDS Patients at Felege-Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia

Table 2

Bivariate and multivariate analysis of factors associated with serum cryptococcal antigenemia among HIV/AIDS patients in Felege-Hiwot Referral Hospital, Bahir Dar, Ethiopia.

VariablePos., N (%)Neg., N (%) valueCOR (95% CI) valueAOR (95% CI)

Sex
 Male7 (44)52 (42)11
 Female9 (56)72 (58)0.8901 (0.377–3)0.3290.4 (0.05–2.7)

Age
 15–243 (19)16 (13)0.3000.4 (0.056–2.4)0.2680.2 (0.007–3.9)
 25–4411 (69)76 (63)0.3540.5 (0.1–2.3)0.5860.6 (0.07–4.6)
 >452 (12)29 (24)1

Marital status
 Unmarried6 (37.5)33 (26.6)0.7450.8 (0.23–2.9)0.6371.7 (0.2–13)
 Married5 (31.2)57 (46)0.4401.7 (0.45–6.2)0.8460.8 (0.1–6.3)
 Others5 (31.2)34 (27.4)1

Educational status
 Illiterate4 (25)36 (29)11
 Literate12 (75)88 (71)0.7370.82 (025–2.7)0.3660.4 (0.04–3.2)

Occupation
 Student1 (6.2)17 (14)11
 House wife2 (12.5)20 (16)0.6760.6 (0.05–7)0.5800.4 (0.012–12)
 Employed11 (68.8)71 (57)0.3690.4 (0.05–3)0.1850.14 (0.008–2.6)
 Jobless2 (12.5)16 (13)0.5540.5 (0.04–5.7)0.3400.19 (0.006–5.9)

Residence
 Urban9 (56)91 (73.4)0.1602 (0.74–6)0.8311.3 (0.2–10)
 Rural7 (44)33 (26.6)1

Bacterial status (n = 79)
 Pulmonary7 (43.8)7 (11.1)0.0010.08 (0.02–0.35)0.0010.04 (0.005–0.25)
 Ex pulmonary5 (31.2)6 (9.5)0.0030.1 (0.02–0.46)0.0060.07 (0.01–0.47)
 BSI4 (25)50 (79.4)1

CD4 status
 <10011 (68.7)7 (5.6)0.0070.05 (0.005–0.4)0.1080.04 (0.001–2)
 100–1503 (18.7)31 (25)0.8000.74 (0.07–7.7)0.3434.6 (0.2–110)
 151–2001 (6.3)14 (11.3)1
 >2001 (6.3)72 (59.4)0.2575 (0.3–87)0.09631 (0.54–1865)

ART status
 On ART3 (18.8)67 (54)1
 ART naïve5 (31.2)38 (30.6)0.1550.34 (0.07–1.5)0.1610.09 (0.004–2.5)
 ART defaulter8 (50)19 (15.3)0.0020.1 (0.026–0.44)0.0190.02 (0.001–0.5)

Note. 1 = as a reference; others, widow and divorced; BSI, bacterial infection isolated by blood culture; AOR, adjusted odds ratio; OR, crude odds ratio; CI, confidence interval.