Prevalence of Cryptococcal Antigenemia and Associated Factors among HIV/AIDS Patients at Felege-Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia
Table 2
Bivariate and multivariate analysis of factors associated with serum cryptococcal antigenemia among HIV/AIDS patients in Felege-Hiwot Referral Hospital, Bahir Dar, Ethiopia.
Variable
Pos., N (%)
Neg., N (%)
value
COR (95% CI)
value
AOR (95% CI)
Sex
Male
7 (44)
52 (42)
1
1
Female
9 (56)
72 (58)
0.890
1 (0.377–3)
0.329
0.4 (0.05–2.7)
Age
15–24
3 (19)
16 (13)
0.300
0.4 (0.056–2.4)
0.268
0.2 (0.007–3.9)
25–44
11 (69)
76 (63)
0.354
0.5 (0.1–2.3)
0.586
0.6 (0.07–4.6)
>45
2 (12)
29 (24)
1
Marital status
Unmarried
6 (37.5)
33 (26.6)
0.745
0.8 (0.23–2.9)
0.637
1.7 (0.2–13)
Married
5 (31.2)
57 (46)
0.440
1.7 (0.45–6.2)
0.846
0.8 (0.1–6.3)
Others
5 (31.2)
34 (27.4)
1
Educational status
Illiterate
4 (25)
36 (29)
1
1
Literate
12 (75)
88 (71)
0.737
0.82 (025–2.7)
0.366
0.4 (0.04–3.2)
Occupation
Student
1 (6.2)
17 (14)
1
1
House wife
2 (12.5)
20 (16)
0.676
0.6 (0.05–7)
0.580
0.4 (0.012–12)
Employed
11 (68.8)
71 (57)
0.369
0.4 (0.05–3)
0.185
0.14 (0.008–2.6)
Jobless
2 (12.5)
16 (13)
0.554
0.5 (0.04–5.7)
0.340
0.19 (0.006–5.9)
Residence
Urban
9 (56)
91 (73.4)
0.160
2 (0.74–6)
0.831
1.3 (0.2–10)
Rural
7 (44)
33 (26.6)
1
Bacterial status (n = 79)
Pulmonary
7 (43.8)
7 (11.1)
0.001
0.08 (0.02–0.35)
0.001
0.04 (0.005–0.25)
Ex pulmonary
5 (31.2)
6 (9.5)
0.003
0.1 (0.02–0.46)
0.006
0.07 (0.01–0.47)
BSI
4 (25)
50 (79.4)
1
CD4 status
<100
11 (68.7)
7 (5.6)
0.007
0.05 (0.005–0.4)
0.108
0.04 (0.001–2)
100–150
3 (18.7)
31 (25)
0.800
0.74 (0.07–7.7)
0.343
4.6 (0.2–110)
151–200
1 (6.3)
14 (11.3)
1
>200
1 (6.3)
72 (59.4)
0.257
5 (0.3–87)
0.096
31 (0.54–1865)
ART status
On ART
3 (18.8)
67 (54)
1
ART naïve
5 (31.2)
38 (30.6)
0.155
0.34 (0.07–1.5)
0.161
0.09 (0.004–2.5)
ART defaulter
8 (50)
19 (15.3)
0.002
0.1 (0.026–0.44)
0.019
0.02 (0.001–0.5)
Note. 1 = as a reference; others, widow and divorced; BSI, bacterial infection isolated by blood culture; AOR, adjusted odds ratio; OR, crude odds ratio; CI, confidence interval.