Serotype Distribution and Antimicrobial Resistance Profile of Haemophilus influenzae Isolated from School Children with Acute Otitis Media

Table. 2

Antimicrobial susceptibility of H. influenzae isolated from nasopharynx of school children with AOM.

Antimicrobials	Susceptible (%)	Intermediate (%)	Resistant (%)	MIC50 (µg/mL)	MIC90 (µg/mL)	MIC range (µg/mL)
LEVO	100	0	0	≤0.03	≤0.03	≤0.03 to 0.5
CLA	82	18	0	8	16	≤0.12 to 16
FAC	96	1	2	≤4	8	≤4 to >16
AXO	100	0	0	≤0.03	≤0.03	≤0.03 to 0,25
AMP^a	86	4	11	0,25	4	≤0.12 to >4
FEP	99	0	1	≤0.12	0,25	≤0.12 to >2
SPX	99	0	1	≤0.03	≤0.03	≤0.03 to 0,5
IMI	100	0	0	≤0.5	≤0.5	≤0.5 to 1
SXT	74	7	19	0.25/4.75	>2/38	≤0.06/1.19 to >2/38
MERO	100	0	0	≤0.06	≤0.06	≤0.06 to 0,25
FUR	100	0	0	1	2	≤0.5 to 4
FIX	100	0	0	≤0.12	≤0.12	≤0.12 to 1
TET	93	1	6	0,5	1	≤0.25 to >4
CHL	94	0	6	≤0.5	1	≤0.5 to >4
A/S2	96	0	4	≤1/0.5	≤1/0.5	≤1/0.5 to >2/1
AMC	99	0	1	≤2/1	≤2/1	≤2/1 to >16/8

^aBreakpoints used for ampicillin: susceptible = ≤1, intermediate = 2, resistant = ≥4. LEVO, levofloxacin; CLA, clarithromycin; FAC, cefaclor; AXO, ceftriaxone; AMP, ampicillin; FEP, cefepime; SPX, sparfloxacin; IMI, imipenem; SXT, trimethoprim/sulfamethoxazole; MERO, meropenem; FUR, cefuroxime; FIX, cefixime; TET, tetracycline; CHL, chloramphenicol; A/S2, ampicillin/sulbactam (2 : 1); AMC, amoxicillin/clavulanic acid (2 : 1).