Review of CRISPR-Cas Systems in Listeria Species: Current Knowledge and Perspectives

Figure 1

Summary of CRISPR-Cas system and potential applications in Listeria. Influence of AcrIIA1 and AcrIIA12 proteins on (a) lytic and (c) lysogenic cycle of Listeria bacteriophages. (b) Overview of common CRISPR-Cas mechanism of action. (d) Possible application of Acr proteins mediating biofilm formation and control. (e) Most common CRISPR-Cas systems in Listeria. (f) CRISPR-Cas as a potential virulence factor in pathobionts.