Papaverine Enhances the Oncolytic Effects of Newcastle Disease Virus on Breast Cancer In Vitro and In Vivo

Table 3

The cotoxic and synergism effects of NDV and papaverine as a combination treatment on normal cells.

Dose NDV	Dose pap	Effect	Combination index CI	Effect
0.1	10.0	0.182	0.35777	Synergism
0.1	25.0	0.208	0.84347	Synergism
0.1	50.0	0.244	1.80122	Antagonism
1.0	10.0	0.203	1.23505	Antagonism
1.0	25.0	0.214	1.74186	Antagonism
1.0	50.0	0.226	2.61146	Antagonism
2.0	10.0	0.18	1.99904	Antagonism
2.0	25.0	0.26	3.15104	Antagonism
2.0	50.0	0.26	4.04236	Antagonism