Standardization of SARS-CoV-2 Nucleic Acid Amplification Techniques by Calibration and Quantification to the First WHO International Standard for SARS-CoV-2 RNA

Table 1

Clinical sensitivity and specificity of the Panther TMA assay compared to Cobas 6800 ORF1a/b and pan-Sarbeco assays.

	Frequency	Percentage	95% CI	95% CI
	(n)	(%)	Lower limit	Upper limit
Sensitivity	31/31	100.0	88.8	100.0
Specificity	27/29	93.1	77.2	99.2
NPV^#	27/27	100.0	87.2	100.0
PPV^&	31/33	93.9	87.2	100.0
Accuracy	58/60	96.7	88.5	99.6

^#PPV = positive predictive value; ^&NPV = negative predictive value; 95% CI = 95% confidence interval.