Research Article
Analysis of Fractional Order Mathematical Model of Hematopoietic Stem Cell Gene-Based Therapy
Table 1
The description of parameters in the model.
| Parameter | Description | Unit |
| | Production rate of uninfected CD4+ T cells | Concentration cells /time unit | | Death rate of uninfected CD4+ T cells | 1/ time unit | | Infection rate | Concentration cells−1/ time unit | | Death rate of infected CD4+ T cells | 1/ time unit | | Effector CTL rate of killing infected CD4+ T cells | Concentration cells−1/ time unit | | Fractions of HSCs that successfully differentiated into functional CTL cells | - | | Proliferation rate of precursor CTL | Concentration cells−2/ time unit | | Fraction of precursor CTL cells that differentiated into effector CTL cells | - | | Death rate of precursor CTL | 1/ time unit | | Death rate of effector CTL | 1/ time unit | | Differentiation rate of CD8+ T lymphocytes | 1/ time unit |
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