Research Article
Analysis of Fractional Order Mathematical Model of Hematopoietic Stem Cell Gene-Based Therapy
Table 4
Parameters value of the model.
| Parameter | Description | Value | Source |
| | Production rate of uninfected CD4+ T cells | 0.2 | [14] | | Death rate of uninfected CD4+ T cells | 0.05 | Assumption | | Infection rate | 0.15 | [14]. | | Death rate of infected CD4+ T cells | 0.8 | [14] | | Effector CTL rate of killing infected CD4+ T cells | 0.016 | [14] | | Fractions of HSCs that successfully differentiated into functional CTL cells | 0.01 | Assumption | | Proliferation rate of precursor CTL | 0.1 | Assumption | | Fraction of precursor CTL cells that differentiated into effector CTL cells | 0.1 | Assumption | | Death rate of precursor CTL | 0.05 | [14] | | Death rate of effector CTL | 0.05 | [14] | | Differentiation rate of CD8+ T cells | 0.005 | Assumption |
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