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International Journal of Nephrology
Volume 2010 (2010), Article ID 391656, 2 pages
Case Report

Use of Hypertonic Continuous Venovenous Hemodiafiltration to Control Intracranial Hypertension in an End-Stage Renal Disease Patient

1Division of Nephrology, Department of Internal Medicine, University of South Florida College of Medicine, Tampa, 33612, USA
2Interventional Neurology Program, Comprehensive Stroke Center, St. Mary's Medical Center, West Palm Beach, 33407, USA
3Section for Neurological Critical Care, Department of Neurology, University of South Florida College of Medicine, Tampa, 33612, USA

Received 4 January 2010; Revised 24 May 2010; Accepted 15 June 2010

Academic Editor: Alejandro Martín-Malo

Copyright © 2010 Stephen I. Rifkin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Continuous venovenous hemodiafiltration (CVVHDF) using solutions designed to maintain hypernatremia is described in an end-stage renal disease (ESRD) patient with cerebral edema (CE) due to an intracerebral hemorrhage (ICH). Hypernatremia was readily achieved and maintained without complication. CVVHDF should be considered as an alternative treatment option in ESRD patients with cerebral edema who require hypertonic saline therapy.