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International Journal of Nephrology
Volume 2011, Article ID 315879, 5 pages
Review Article

The Impact of Fructose on Renal Function and Blood Pressure

1Department of Nephrology, Hypertension and Internal Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, ul. Skłodowskiej-Curie 9, 85-094 Bydgoszcz, Poland
2Division of Renal Diseases and Hypertension, University of Colorado Denver, Denver, CO 80045, USA

Received 20 April 2011; Revised 17 June 2011; Accepted 17 June 2011

Academic Editor: Franca Anglani

Copyright © 2011 Marek Kretowicz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Fructose is a sugar present in sucrose, high-fructose corn syrup, honey, and fruits. Fructose intake has increased markedly in the last two centuries, primarily due to increased intake of added sugars. Increasing evidence suggests that the excessive intake of fructose may induce fatty liver, insulin resistance, dyslipidemia, hypertension, and kidney disease. These studies suggest that excessive intake of fructose might have an etiologic role in the epidemic of obesity, diabetes, and cardiorenal disease.