International Journal of Nephrology / 2011 / Article / Tab 2

Clinical Study

Effects of Moderate-to-Severe Impairment of the Estimated Glomerular Filtration Rate and of Proteinuria on the Central Hemodynamics and Arterial Stiffness in Middle-Aged Healthy Japanese Men

Table 2

Clinical characteristics of the study subjects classified by the presence/absence of proteinuria.

Pro (+)Pro (−) -valueeGFR < 60eGFR ≥ 60 value

Number652179482196
Age (y) .69 <.01
Height (cm) .21 .92
BMI <.05 <.05
WC (cm) <.05 .09
Smoking (%)30 (46)677 (31)<.017 (15)700 (32)<.01
ALC (N/LM/H)(%)12/34/19 (18/52/30)279/1352/548 (13/62/25).255/32/11 (10/67/23)286/1354/556 (13/62/25).76
SBP (mmHg) <.05 <.01
DBP (mmHg) <.05 <.01
Pulse rate (bpm) <.05 .07
baPWV (m/s) <.01 <.01
radial AI (%) <.05 .12
SBP 2 (mmHg) <.01 <.01
TC (mmol/L) .19 <.01
HDL (mmol/L ) <.01 .16
TG (mmol/L) .31 <.01
FPG (mmol/Ll) .12 <.01
eGFR (mL/min per 1.73 m2) .10 <.01
eGFR <60 (%)1 (1.5)64 (2.9).59
Proteinuria (%)1 (2.0)47 (2.1).75

Abbreviations. Pro (+): subjects with proteinuria; Pro (−): subjects without proteinuria; eGFR < 60: subjects with eGFR of 15 to 59 mL/min per 1.73 m2; eGFR ≥ 60: subjects with eGFR ≥ 60 mL/min per 1.73 m2; BMI: body mass index; WC: waist circumference; smoking: number of subjects who were smoking; ALC: (N: nondrinker, LM: light-to-moderate drinker (ethanol intake: 1–29 g/day), and H: heavy drinker (ethanol intake: ≥30 g/day)); SBP: systolic blood pressure; DBP: diastolic blood pressure; baPWV: brachial-ankle pulse wave velocity; radial AI: radial augmentation index; SBP2: second peak of the radial pressure waveform; TC: serum total cholesterol; HDL: serum high-density lipoprotein cholesterol; TG: serum triglycerides; FPG: fasting plasma glucose; eGFR: estimated glomerular filtration rate; eGFR < 60 mL/min per 1.73 m2: number of subjects with eGFR < 60 mL/min per 1.73 m2; proteinuria: number of subjects with proteinuria.

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