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International Journal of Nephrology
Volume 2011 (2011), Article ID 471214, 7 pages
http://dx.doi.org/10.4061/2011/471214
Review Article

Dilemma of HCV Infection in Renal Transplant Recipients

Urology and Nephrology Center, Mansoura University, Gomhoria Street, Mansoura, Egypt

Received 14 November 2010; Revised 19 January 2011; Accepted 5 March 2011

Academic Editor: Ayman Karkar

Copyright © 2011 Osama Ashry Ahmed Gheith. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Hepatitis C virus, which usually starts during dialysis therapy, is currently the main cause of chronic liver disease in such population. The majority of patients acquired the disease through intravenous drug use or blood transfusion, with some risk factors identified. In this review we are dealing with the effect of renal transplantation on HCV infection and HCV-related complications after renal transplantation. Moreover, we are discussing the therapeutic options of HCV infection before and after renal transplantation, the best immunosuppressive protocol and lastly graft and patient survival in patients who underwent pretransplant management vs. those who were transplanted without treatment.