B-Type Natriuretic Peptide in the Critically Ill with Acute Kidney Injury

Table 3

Median of creatinine and BNP during 48 hours of ICU stay for patients with or without AKI on admission to ICU. The increase in BNP of AKI patients is significant (𝑃=.012).

		AKI; (5)	No-AKI; (21)	𝑃value
Serum creatinine, mg/dL	Baseline	1.85; (1.70 to 3.85)	0.82; (0.68 to 1.01)	.001
	24 hours	2.49; (1.60 to 4.53)	0.79; (0.64 to 0.97)	.001
	48 hours	2.14; (1.47 to 5.24)	0.78; (0.63 to 0.89)	.004
Plasma BNP, pg/mL	Baseline	510; (369 to 690)	197; (42 to 485)	.06
	24 hours	865; (344 to 948)	148; (47 to 447)	.047
	48 hours	1380; (985 to 1625)	131; (43 to 297)	<.001

BNP: B-type or brain natriuretic peptide.
ICU: Intensive care unit.
AKI: Acute kidney injury.