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International Journal of Nephrology
Volume 2012 (2012), Article ID 106914, 6 pages
Review Article

Physical Activity and Blood Lipids and Lipoproteins in Dialysis Patients

1Department of Health and Nutrition, Faculty of Health Management, Nagasaki International University, 2825-7 Huis Ten Bosch, Sasebo-shi, Nagasaki 859-3298, Japan
2School of Nursing, Fukuyama Heisei University, 117-1 Masado Kamiiwanari, Miyuki-cho, Fukuyama-shi, Hiroshima 720-0001, Japan
3Faculty of Life Sciences, Seika Women’s Junior College, 2-12-1 Minami Hachiman-cho, Hakata-ku, Fukuoka 812-0886, Japan

Received 24 January 2012; Accepted 2 August 2012

Academic Editor: Jaime Uribarri

Copyright © 2012 Hiroyuki Imamura et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The relationship between physical activity and blood lipids and lipoproteins in dialysis patients is reviewed in the context of the potentially confounding factors such as nutritional intake, cigarette smoking, obesity, alcohol intake, and physical activity levels in the general population and additional confounding factors such as mode of dialysis and diabetes in dialysis patients. The known associations in the general population of physical activity with high-density-lipoprotein cholesterol subfractions and apolipoprotein A-I are more pronounced in hemodialysis patients than in peritoneal dialysis patients even after adjusting for these confounding factors. Examining studies on the effects of physical activity on blood lipids and lipoproteins, the most consistent observation is the noted decrease in triglycerides and increase in high-density-lipoprotein cholesterol and insulin sensitivity in hemodialysis patients. The changes in lipids and lipoproteins in hemodialysis patients could be caused by changes in activity levels of lipoprotein lipase, insulin sensitivity, and/or glucose metabolism. Future research investigating the relationship between physical activity and blood lipids and lipoproteins in dialysis patients should direct research towards the underlying mechanisms for changes in blood lipids and lipoproteins.